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A digestive tract cancer that most often occurs in the stomach or small intestine.

Gastrointestinal stromal tumor, also called GIST, is a digestive tract cancer. It starts in special nerve cells in the walls of the digestive organs. This cancer happens most often in the stomach or small intestine.

Symptoms may include pain or swelling in the belly, nausea, vomiting, and fatigue.

Treatments include surgery and targeted therapy medicines.